The nurse is caring for a patient who has a prescription for piperacillin 1.5 grams iM. The pharmacist sends a vial containing 2000 mg. The directions for reconstitution state to add 4 milliliters of normal saline to obtain a concentration of 1 gram per 2.5 mL. How many milliliters of the reconstituted drug should the nurse administer with each dose? (Record your answer using 2 decimal places)

To calculate how many milliliters (mL) of the reconstituted drug the nurse should administer, we can use the following steps:

### Step 1: Convert the prescribed dose to milligrams (mg)
The prescription is for 1.5 grams. Since 1 gram = 1000 mg:
\[
1.5 \, \text{grams} = 1.5 \times 1000 = 1500 \, \text{mg}
\]
The prescribed dose is 1500 mg.

### Step 2: Determine the concentration of the reconstituted solution
The instructions state that after adding 4 mL of saline, the concentration is 1 gram (1000 mg) per 2.5 mL of solution.

### Step 3: Set up the proportion
We know that:
\[
\frac{1000 \, \text{mg}}{2.5 \, \text{mL}} = \frac{1500 \, \text{mg}}{x \, \text{mL}}
\]
Now, solve for \(x\), the volume in milliliters to administer:
\[
x = \frac{1500 \times 2.5}{1000} = \frac{3750}{1000} = 3.75 \, \text{mL}
\]

### Answer:
The nurse should administer **3.75 mL** of the reconstituted drug for each dose.

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Would you like further details on the steps or additional clarification? Here are some related questions you might consider:

1. How do you convert between grams and milligrams?
2. What is the significance of the reconstitution process in medication preparation?
3. How would you calculate the volume if the concentration was different?
4. Why is it important to record the answer using two decimal places?
5. What safety precautions should be taken when administering intramuscular injections?

**Tip:** Always double-check the concentration of the medication after reconstitution to ensure the correct dosage is being administered.

The nurse is caring for a patient who has a prescription for piperacillin 1.5 grams IM. The pharmacist sends a vial containing 2000 mg. The directions for reconstitution state to add 4 milliliters of normal saline to obtain a concentration of 1 gram per 2.5 mL. How many milliliters of the reconstituted drug should the nurse administer with each dose? (Record your answer using 2 decimal places).

Learn how to calculate the dosage for piperacillin when the prescribed dose is 1.5 grams, and the vial contains 2000 mg with a concentration of 1 gram per 2.5 mL. This step-by-step solution involves unit conversion and proportions, suitable for nursing and pharmacy students in Grades 10-12.

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