Let's break down the expression step by step:

$-2 \cdot (-6) + \left(\frac{-64}{8}\right)$

1. First, calculate $-2 \cdot (-6)$: $-2 \cdot (-6) = 12$

2. Next, calculate $\frac{-64}{8}$: $\frac{-64}{8} = -8$

3. Now, add the results: $12 + (-8) = 4$

So, the final result is:

$4$

Would you like any additional details on this? Here are 5 related questions:

1. How do you handle negative numbers in multiplication?
2. What happens when you divide a negative number by a positive number?
3. Can you explain the distributive property of multiplication over addition?
4. What is the order of operations in complex expressions?
5. How do negative signs affect addition and subtraction?

Tip: Always perform multiplication and division before addition and subtraction when following the order of operations (PEMDAS).