To solve the expression $5 - (-6) \times 9$, follow the order of operations (PEMDAS: Parentheses, Exponents, Multiplication and Division (from left to right), Addition and Subtraction (from left to right)).

1. Start by simplifying the negative sign: $5 - (-6) \times 9 = 5 + 6 \times 9$ (Since subtracting a negative number is the same as adding the positive version of the number.)

2. Now multiply $6 \times 9$: $5 + 54$

3. Finally, add $5 + 54$: $59$

So, $5 - (-6) \times 9 = 59$.

Would you like further clarification or details?

Here are five related questions:

1. What happens if you replace $-6$ with $-7$ in the original expression?
2. How do parentheses affect the order of operations in expressions?
3. Can you solve $7 - (-5) \times 8$?
4. What is the result of $10 + (-5) \times (-3)$?
5. How do you handle multiple negative signs in an expression?

Tip: Always follow the order of operations carefully to avoid mistakes, especially with negative numbers!