Let's break down the expression step by step:

$-2 - 3 - 5 - 7 + \frac{8}{-2}$

Step 1: Perform the division

$\frac{8}{-2} = -4$

Now the expression becomes: $-2 - 3 - 5 - 7 - 4$

Step 2: Combine all the terms

$-2 - 3 = -5$ $-5 - 5 = -10$ $-10 - 7 = -17$ $-17 - 4 = -21$

So, the result is: $\boxed{-21}$

Would you like more details or have any questions?

Here are 5 related questions for practice:

1. What is the result of $10 - 5 \times 2 \div (-1)$?
2. Simplify the expression: $-6 + 4 - 9 + 3 \div (-3)$.
3. What is $-2 \times (5 + 7) + 8 \div 4$?
4. Evaluate $3^2 - 4 \times 5 + 6 \div (-2)$.
5. What is the result of $-4 + 12 \div (-3) \times 2$?

Tip: Always follow the order of operations (PEMDAS: Parentheses, Exponents, Multiplication and Division (left to right), Addition and Subtraction (left to right)).