Let's break down the expression step by step:

The expression is:

\[
\frac{-16}{\frac{8}{-2}}
\]

### Step 1: Simplify the denominator
The denominator is \(\frac{8}{-2}\). Simplifying that:

\[
\frac{8}{-2} = -4
\]

### Step 2: Rewrite the expression
Now the expression becomes:

\[
\frac{-16}{-4}
\]

### Step 3: Simplify the fraction
Now divide \(-16\) by \(-4\):

\[
\frac{-16}{-4} = 4
\]

### Final Answer: 
The result is:

\[
4
\]

Would you like any further details or explanations on this?

Here are 5 related questions:
1. How do you simplify complex fractions?
2. What happens if there is a negative sign inside the fraction?
3. Can you have multiple operations in both the numerator and denominator?
4. How do you divide fractions?
5. What are the properties of division with negative numbers?

**Tip:** Always simplify the numerator and denominator separately before dividing them for more accuracy.

Learn how to simplify the fraction 16/[8/(-2)] step by step, including handling division of negative numbers and simplifying fractions. This problem focuses on understanding fraction division and negative signs, making it ideal for students in Grades 6-8.

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