Math Problem Statement

. A hospital wants to determine the appropriate dosage of a medication for a certain condition. The effectiveness of the medication is known to follow a normal distribution with a mean dosage of 150mg and a standard deviation of 20 mg. What percentage of patients should receive a dosage between 130 mg and 170 mg for the medication to be effective?

Solution:

Solution

To determine what percentage of patients should receive a dosage between 130 mg and 170 mg, given that the effectiveness of the medication follows a normal distribution with a mean of 150 mg and a standard deviation of 20 mg, we can use the properties of the normal distribution.

Step-by-Step Solution:

  1. Identify the parameters of the normal distribution:

    • Mean (μ\mu) = 150 mg
    • Standard deviation (σ\sigma) = 20 mg
  2. Standardize the dosage values (convert to z-scores): We need to find the z-scores corresponding to the dosages of 130 mg and 170 mg. The formula to convert a value XX to a z-score is: Z=XμσZ = \frac{X - \mu}{\sigma}

    For X=130X = 130 mg: Z130=13015020=2020=1Z_{130} = \frac{130 - 150}{20} = \frac{-20}{20} = -1

    For X=170X = 170 mg: Z170=17015020=2020=1Z_{170} = \frac{170 - 150}{20} = \frac{20}{20} = 1

  3. Use the standard normal distribution table (or calculator) to find the probability corresponding to these z-scores:

    • The z-score of -1 corresponds to a cumulative probability of approximately 0.1587.
    • The z-score of 1 corresponds to a cumulative probability of approximately 0.8413.
  4. Calculate the percentage between these two z-scores: The percentage of patients who should receive a dosage between 130 mg and 170 mg is the difference between the cumulative probabilities at the two z-scores: P(130X170)=P(Z1)P(Z1)=0.84130.1587=0.6826P(130 \leq X \leq 170) = P(Z \leq 1) - P(Z \leq -1) = 0.8413 - 0.1587 = 0.6826

  5. Convert the result to a percentage: 0.6826×100=68.26%0.6826 \times 100 = 68.26\%

Final Answer:

Approximately 68.26% of patients should receive a dosage between 130 mg and 170 mg for the medication to be effective.


Do you have any questions or need further details on the calculation? Here are some related questions:

  1. How do you calculate z-scores for values outside the range of the standard normal distribution?
  2. What is the significance of the mean and standard deviation in a normal distribution?
  3. How would the percentage change if the standard deviation was 15 mg instead of 20 mg?
  4. How can we determine the dosage range for 95% of the population?
  5. Can we apply the same method if the distribution is not normal?

Tip: In a normal distribution, about 68% of the data falls within one standard deviation of the mean. This is useful for quick approximations.

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Math Problem Analysis

Mathematical Concepts

Statistics
Normal Distribution
Z-Scores
Probability

Formulas

Z = (X - μ) / σ
P(a ≤ X ≤ b) = P(Z ≤ z_b) - P(Z ≤ z_a)
Percentage = Probability × 100

Theorems

68-95-99.7 Rule
Properties of Normal Distribution

Suitable Grade Level

College Level, Advanced High School (AP Statistics)