Math Problem Statement

A pharmaceutical company is testing the effectiveness of a new drug for lowering cholesterol. As part of this trial, they wish to determine whether there is a difference between the effectiveness for women and men. At = 0.05, what is an appropriate test value? Use p-value method. Women Men Sample size 60 50 Mean effectiveness 4.4 3.9 Population variance 3.6 3.6

Solution

To determine whether there is a significant difference between the effectiveness of the drug for women and men, we can use a two-sample z-test because the population variances are known. Let's go through the steps for solving this problem.


Step 1: Define Hypotheses

  • Null Hypothesis (H0H_0): There is no difference in effectiveness between women and men (μw=μm\mu_w = \mu_m).
  • Alternative Hypothesis (HaH_a): There is a difference in effectiveness between women and men (μwμm\mu_w \neq \mu_m).

Step 2: Test Statistic Formula

The formula for the two-sample z-test is:

z=xˉwxˉmσ2nw+σ2nmz = \frac{\bar{x}_w - \bar{x}_m}{\sqrt{\frac{\sigma^2}{n_w} + \frac{\sigma^2}{n_m}}}

Where:

  • xˉw\bar{x}_w and xˉm\bar{x}_m are the sample means for women and men.
  • σ2\sigma^2 is the common population variance.
  • nwn_w and nmn_m are the sample sizes for women and men.

Step 3: Plug in Values

Given:

  • Women: nw=60n_w = 60, xˉw=4.4\bar{x}_w = 4.4
  • Men: nm=50n_m = 50, xˉm=3.9\bar{x}_m = 3.9
  • Common variance: σ2=3.6\sigma^2 = 3.6

The test statistic is:

z=4.43.93.660+3.650z = \frac{4.4 - 3.9}{\sqrt{\frac{3.6}{60} + \frac{3.6}{50}}}

First, calculate the denominator:

3.660+3.650=0.06+0.072=0.1320.363\sqrt{\frac{3.6}{60} + \frac{3.6}{50}} = \sqrt{0.06 + 0.072} = \sqrt{0.132} \approx 0.363

Now calculate zz:

z=4.43.90.363=0.50.3631.377z = \frac{4.4 - 3.9}{0.363} = \frac{0.5}{0.363} \approx 1.377


Step 4: Find the p-value

For a two-tailed test with z=1.377z = 1.377, use a standard normal distribution table or a calculator:

p-value=2×P(Z>1.377)\text{p-value} = 2 \times P(Z > 1.377)

Using the standard normal table:

P(Z>1.377)0.084P(Z > 1.377) \approx 0.084

Thus:

p-value=2×0.084=0.168\text{p-value} = 2 \times 0.084 = 0.168


Step 5: Conclusion

Compare the p-value to the significance level (α=0.05\alpha = 0.05):

  • Since 0.168>0.050.168 > 0.05, we fail to reject the null hypothesis.

Interpretation:

There is not enough evidence to conclude that the drug's effectiveness differs between women and men at the 5% significance level.


Do you want further clarification or have any specific questions? Here are 5 related questions to expand on this:

  1. How is the p-value related to the level of significance in hypothesis testing?
  2. What would happen if the population variances were unequal?
  3. Can this test be conducted as a one-tailed test? If so, how would the conclusion change?
  4. What are the assumptions of the two-sample z-test, and are they met in this case?
  5. How would increasing the sample size affect the test's sensitivity?

Tip: Always verify whether population variances are equal or known before choosing a z-test or t-test.

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Math Problem Analysis

Mathematical Concepts

Hypothesis Testing
Two-Sample Z-Test
P-Value Calculation

Formulas

z = (x̄₁ - x̄₂) / sqrt(σ²/n₁ + σ²/n₂)
P(Z > z) for p-value in standard normal distribution

Theorems

Central Limit Theorem
Properties of Standard Normal Distribution

Suitable Grade Level

Undergraduate Statistics