The expression given is:

$-4 + 5 - 7 + 10$

Let's solve it step by step:

1. First, add $-4$ and $5$: $-4 + 5 = 1$

2. Next, subtract $7$: $1 - 7 = -6$

3. Finally, add $10$: $-6 + 10 = 4$

So, the result is:

$\boxed{4}$

Would you like any further details or have any questions?

Here are 5 related questions:

1. What is the sum of $-3 + 7 - 9 + 8$?
2. How do you simplify $-5 + 6 - 8 + 9$?
3. What happens when you subtract a negative number in a similar problem?
4. How would the result change if the order of operations were altered?
5. Can you think of another way to group the terms to simplify?

Tip: Always handle negative and positive signs carefully when combining numbers!