To simplify the expression $4(2x - 10)$, we apply the distributive property:

$4(2x - 10) = 4 \times 2x - 4 \times 10 = 8x - 40$

So, the simplified expression is:

$8x - 40$

Would you like any further details or clarifications? Here are 5 related questions to explore further:

1. How do you solve equations involving parentheses like this one?
2. What is the next step if you have an equation set equal to a number, like $8x - 40 = 0$?
3. How do you factor an expression like $8x - 40$?
4. How can you simplify more complex expressions with multiple variables?
5. What is the distributive property, and why is it important in algebra?

Tip: When simplifying expressions, always distribute multiplication over addition or subtraction first before combining like terms!