Math Problem Statement

A rare form of malignant tumor occurs in 11 children in a​ million, so its probability is 0.000011. Four cases of this tumor occurred in a certain​ town, which had 15,659 children.

a. Assuming that this tumor occurs as​ usual, find the mean number of cases in groups of 15,659 children.

b. Using the unrounded mean from part ​(a​), find the probability that the number of tumor cases in a group of 15,659 children is 0 or 1.

c. What is the probability of more than one​ case?

d. Does the cluster of four cases appear to be attributable to random​ chance? Why or why​ not?

Solution

Let's go through each part of the problem.

Part (a): Finding the Mean Number of Cases

To find the mean number of cases, we can use the formula for the expected value μ=n×p\mu = n \times p, where:

  • n=15,659n = 15,659 (the number of children in the town)
  • p=0.000011p = 0.000011 (the probability of one child having the tumor)

μ=n×p=15,659×0.000011\mu = n \times p = 15,659 \times 0.000011

Calculating this:

μ=0.172249\mu = 0.172249

So, the mean number of cases in groups of 15,659 children is approximately 0.172.

Part (b): Probability that the Number of Tumor Cases is 0 or 1

With the mean μ=0.172249\mu = 0.172249, we can use a Poisson distribution to approximate the probabilities, since the probability of occurrence is very low and the mean is small.

The Poisson probability formula is: P(X=k)=eμμkk!P(X = k) = \frac{e^{-\mu} \mu^k}{k!} where XX is the number of cases and μ=0.172249\mu = 0.172249.

Probability of 0 cases: P(X=0)=e0.1722490.17224900!=e0.1722490.8419P(X = 0) = \frac{e^{-0.172249} \cdot 0.172249^0}{0!} = e^{-0.172249} \approx 0.8419

Probability of 1 case: P(X=1)=e0.1722490.17224911!0.1451P(X = 1) = \frac{e^{-0.172249} \cdot 0.172249^1}{1!} \approx 0.1451

Adding these probabilities gives us the probability of 0 or 1 cases: P(X=0 or 1)=P(X=0)+P(X=1)0.8419+0.1451=0.987P(X = 0 \text{ or } 1) = P(X = 0) + P(X = 1) \approx 0.8419 + 0.1451 = 0.987

So, the probability of observing 0 or 1 cases is approximately 0.987.

Part (c): Probability of More than One Case

To find the probability of more than one case, we can use the complement of the probability of 0 or 1 cases.

P(X>1)=1P(X=0 or 1)=10.987=0.013P(X > 1) = 1 - P(X = 0 \text{ or } 1) = 1 - 0.987 = 0.013

Thus, the probability of more than one case is approximately 0.013.

Part (d): Analyzing the Cluster of Four Cases

Given that the probability of observing more than one case is only 0.013 (or 1.3%), the occurrence of four cases is highly unlikely if the tumor occurrences are purely random. Therefore, the cluster of four cases does not appear to be attributable to random chance alone, suggesting that there might be an external factor or cause contributing to the unusually high occurrence in this town.


Would you like more details on any step or have any other questions?

Related Questions

  1. How is the Poisson distribution useful in analyzing rare events?
  2. Could the result in part (d) justify further epidemiological study in this town?
  3. What other factors might explain an unusually high rate of rare diseases in a specific location?
  4. How would a larger population size affect the mean and probabilities?
  5. What is the relationship between probability and statistical significance in public health studies?

Tip:

For rare-event probability problems, the Poisson distribution provides a useful approximation when the sample size is large, and individual probabilities are small.

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Math Problem Analysis

Mathematical Concepts

Probability
Poisson Distribution
Expected Value

Formulas

Expected Value (Mean) μ = n × p
Poisson Probability Formula P(X = k) = (e^(-μ) * μ^k) / k!

Theorems

Poisson distribution for rare events approximation

Suitable Grade Level

Grades 11-12