The multiplication of 48,578 by 43,765 is:

\[
48,578 \times 43,765 = 2,124,688,270
\]

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Here are some related questions you might find interesting:

1. How would you multiply two large numbers using the long multiplication method?
2. What are the properties of multiplication that can simplify calculations?
3. Can you estimate the product of two large numbers by rounding them first?
4. How does multiplication work in different numeral systems, like binary?
5. What are some real-world applications where large number multiplication is crucial?

**Tip:** When multiplying large numbers, it's often helpful to break down the numbers into smaller, more manageable parts, or to use estimation to verify your answer quickly.

Learn how to multiply 48,578 by 43,765 with a detailed step-by-step solution. This problem covers the multiplication of large numbers using long multiplication method. Suitable for students in Grades 5-8.

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