Math Problem Statement
Salicylate is active in aspirin. The following table shows the amount of salicylate in the bloodstream of a certain person t minutes after ingesting 200 milligrams of aspirin. Time (min) 0 20 40 60 80 100 120 Salicylate (mg) 200 177 157 144 123 114 99 Use exponential regression to write an exponential decay function for A, the milligrams of salicylate remaining t minutes after ingesting the aspirin. Round constants to the nearest thousandth. A =
Use the model to predict the amount of salicylate (in mg) remaining 4 hrs after ingesting the aspirin. Round to the nearest whole number.
Solution
To find the exponential decay function that models the amount of salicylate in the bloodstream over time , we can use an exponential regression on the given data. The exponential model has the form:
where:
- is the initial amount of salicylate (in this case, 200 mg).
- is the decay constant, which we’ll determine through regression.
- is the time in minutes.
Step 1: Fit an Exponential Decay Model Using Exponential Regression
Given data points:
Time (t, minutes) | Salicylate (A, mg) |
---|---|
0 | 200 |
20 | 177 |
40 | 157 |
60 | 144 |
80 | 123 |
100 | 114 |
120 | 99 |
Using exponential regression on this data, we find the values for and .
Through calculation or a calculator with regression capabilities, the model we obtain is approximately:
(Values may vary slightly depending on regression method, but and are typical for this data.)
Step 2: Predict the Amount of Salicylate After 4 Hours (240 Minutes)
To predict the amount of salicylate after 4 hours, we substitute (since 4 hours = 240 minutes) into the model:
Calculating the exponent:
Using :
Rounding to the nearest whole number:
Final Answer:
- Exponential Decay Function:
- Predicted Amount of Salicylate after 4 Hours: Approximately 77 mg
Would you like to see more details on the regression process or have any questions?
Here are five related questions for further exploration:
- How would the decay model change if a different initial dose was ingested?
- Can we use this model to predict salicylate levels beyond 4 hours? What assumptions would we make?
- What effect does changing the decay constant have on the model?
- How does exponential decay differ from linear decay in pharmacokinetics?
- Could this model apply to other drugs with similar decay rates?
Tip: Exponential decay models are often used in pharmacokinetics to predict how quickly drugs are metabolized and removed from the bloodstream.
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Math Problem Analysis
Mathematical Concepts
Exponential Decay
Regression Analysis
Rounding Constants
Formulas
A = A_0 e^(kt)
e^(-kt)
Theorems
Exponential Decay Model
Suitable Grade Level
Grades 10-12
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