The expression in the image asks to find the value of $2 + 4x$ when $x = 4$.

Let's substitute $x = 4$ into the expression:

$2 + 4x = 2 + 4(4)$

Now calculate:

$2 + 16 = 18$

So, the value of $2 + 4x$ when $x = 4$ is 18.

Would you like further details or explanations? Here are some related questions for practice:

1. What is the value of $3 + 5x$ when $x = 3$?
2. How would the expression $2 + 4x$ change if $x = -2$?
3. If $x = 7$, what is the value of $2 + 4x$?
4. Can you solve $5x + 6 = 26$ for $x$?
5. How does changing the coefficient of $x$ from 4 to 5 affect the expression?

Tip: Always substitute values carefully into algebraic expressions, and remember the order of operations (PEMDAS).