To simplify the expression $-2.5(4x - 3)$, we'll distribute $-2.5$ to both terms inside the parentheses.

$-2.5(4x - 3) = (-2.5 \times 4x) + (-2.5 \times -3)$

Now, calculate each part:

$-2.5 \times 4x = -10x$ $-2.5 \times -3 = 7.5$

Thus, the simplified expression is:

$-10x + 7.5$

Would you like more details or have any questions?

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Here are some related problems for practice:

1. Simplify: $3(2x - 5)$
2. Simplify: $-4(5y + 6)$
3. Distribute and simplify: $6.5(3x - 2)$
4. Combine like terms: $-7x + 3 - 4x + 8$
5. Simplify: $2.5(x - 4) + 3x$

Tip: When distributing a negative number, always be cautious of the signs when multiplying.