Math Problem Statement

In a large clinical​ trial, 400,321 children were randomly assigned to two groups. The treatment group consisted of 201,051 children given a vaccine for a certain​ disease, and 37 of those children developed the disease. The other 199,270 children were given a​ placebo, and 130 of those children developed the disease. Consider the vaccine treatment group to be the first sample. Complete parts​ (a) through​ (d) below. Question content area bottom Part 1 a. Assume that a 0.100.10 significance level will be used to test the claim that p 1p1less than<p 2p2. Which is​ better: A hypothesis test or a confidence​ interval? A hypothesis test is better. Part 2 b. In​ general, when dealing with inferences for two population​ proportions, which two of the following are​ equivalent: confidence interval​ method; P-value​ method; critical value​ method? Upper P dash value method and critical value methodP-value method and critical value method are​ equivalent, in that they will always lead to the same conclusion. Both of these methods use a standard deviation based on the assumption that the two population proportions are equal, whereas the other method uses a standard deviation based on estimated values of the population proportions. Part 3 c. If a 0.100.10 significance level is to be used to test the claim that p 1p1less than<p 2p2​, what confidence level should be​ used? 8080​% ​(Type an integer or a​ decimal.) Part 4 d. If the claim in part​ (c) is tested using this sample​ data, we get this confidence​ interval: negative 0.000551−0.000551less than<p 1p1minus−p 2p2less than<negative 0.000385−0.000385. What does this confidence interval suggest about the​ claim? Because the confidence interval ▼

▼ there ▼ a significant difference between the two proportions. Because the confidence interval consists ▼

▼ it appears that the first proportion is ▼ the second proportion. There is ▼ evidence to support the claim that the rate of polio is less for children given the vaccine than it is for children given a placebo.

Solution

Let's solve each part of the problem step-by-step.

Part 1 (a)

Question: Assume that a 0.10 significance level will be used to test the claim that p1<p2p_1 < p_2. Which is better: a hypothesis test or a confidence interval?

Answer: A hypothesis test is better.

Reasoning: A hypothesis test is more appropriate when testing a specific claim about the population proportions, in this case, p1<p2p_1 < p_2.

Part 2 (b)

Question: In general, when dealing with inferences for two population proportions, which two of the following are equivalent: confidence interval method, P-value method, critical value method?

Answer: P-value method and critical value method are equivalent.

Reasoning: Both the P-value method and the critical value method use a standard deviation based on the assumption that the two population proportions are equal, and they will always lead to the same conclusion. The confidence interval method uses a standard deviation based on estimated values of the population proportions.

Part 3 (c)

Question: If a 0.10 significance level is to be used to test the claim that p1<p2p_1 < p_2, what confidence level should be used?

Answer: 90%

Reasoning: For a one-tailed test at the 0.10 significance level, the corresponding confidence level for the confidence interval is 90%.

Part 4 (d)

Question: If the claim in part (c) is tested using this sample data, we get this confidence interval: 0.000551<p1p2<0.000385-0.000551 < p_1 - p_2 < -0.000385. What does this confidence interval suggest about the claim?

Answer:

  • Because the confidence interval does not contain zero, there is a significant difference between the two proportions.
  • Because the confidence interval consists of only negative values, it appears that the first proportion (p1p_1) is less than the second proportion (p2p_2).
  • There is sufficient evidence to support the claim that the rate of the disease is less for children given the vaccine than it is for children given a placebo.

Summary:

To summarize the answers for each part:

  • (a) A hypothesis test is better.
  • (b) P-value method and critical value method are equivalent.
  • (c) 90%
  • (d) There is sufficient evidence to support the claim that the rate of the disease is less for children given the vaccine than it is for children given a placebo.

Would you like more details or have any questions about these parts?

Here are 5 more questions you might ask:

  1. How do you calculate the confidence interval for two population proportions?
  2. What are the assumptions required for conducting a hypothesis test for two proportions?
  3. Can you explain the difference between a one-tailed and a two-tailed test?
  4. How do you interpret the P-value in the context of a hypothesis test?
  5. What is the relationship between the significance level and the confidence level?

Tip: When interpreting confidence intervals, always check whether zero is included in the interval. If zero is not included, it suggests a significant difference between the proportions.

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Math Problem Analysis

Mathematical Concepts

Hypothesis Testing
Confidence Intervals
Two Proportions

Formulas

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Theorems

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Suitable Grade Level

Advanced College Level