Determine the amount of each ingredient needed to make the mixture.

You have: 5mg tablets

Ingredient	Formula Quantity	Amount Used
Tablets 10mg	10	Answer

Tablets
Levigating agent	10mL	Answer

mL
Vehicle	qs 100mL	qs 50mL

To solve this, we will determine how much of each ingredient is needed for the mixture based on the given information.

We know the following:

- You have 5 mg tablets.
- You are working with a mixture involving **10 mg tablets**.
- The total mixture volume is **50 mL** (qs 50 mL of vehicle).

### 1. **Amount of Tablets (10 mg) Required:**
The formula suggests using **10 tablets of 10 mg** each. Since you're using 5 mg tablets instead of 10 mg tablets, you will need to double the number of tablets to maintain the same total amount of active ingredient.

Thus, the amount of 5 mg tablets required is:
\[
\text{Tablets} = 10 \times 2 = 20 \text{ tablets}
\]

### 2. **Levigating Agent (mL):**
The formula specifies using **10 mL** of levigating agent. Since there is no change to this, you will use exactly **10 mL** of the levigating agent.

### 3. **Vehicle:**
The formula calls for a **qs (quantity sufficient) to 100 mL**, but your mixture requires only **50 mL** of the total volume. So, after accounting for the tablets and levigating agent, you will add enough vehicle to bring the total volume to **50 mL**.

### Final Summary:

- **Tablets (5 mg):** 20 tablets
- **Levigating Agent:** 10 mL
- **Vehicle:** qs to 50 mL

Do you want more details or have any questions?

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Here are 5 questions related to this:

1. How does using different tablet strengths affect formulation?
2. What is the purpose of a levigating agent in this mixture?
3. Can the vehicle be any specific liquid, or does it need to be a particular type?
4. Why do we use "qs" to a specific volume in pharmaceutical formulations?
5. How would you adjust the formula for a different total volume (e.g., 100 mL)?

**Tip:** When substituting ingredients with different strengths, always adjust the quantity to maintain the same active ingredient dosage.

Determine the amount of each ingredient needed to make the mixture.

Learn how to calculate the correct amount of each ingredient for a pharmaceutical mixture using 5 mg tablets instead of 10 mg tablets. This guide covers the math behind adjusting proportions, unit conversions, and determining the volume of levigating agents and vehicles. Suitable for Grades 9-12.

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